Kukho imithombo emibini ephambili yongcoliseko kwigumbi lokucoca: amasuntswana kunye nemicroorganisms, enokubangelwa zizinto zabantu kunye nezendalo, okanye imisebenzi enxulumene noko kwinkqubo. Ngaphandle kweenzame ezingcono, ungcoliseko lusaza kungena kwigumbi lokucoca. Abaphathi abathile abaqhelekileyo abaqhelekileyo babandakanya imizimba yabantu (iiseli, iinwele), izinto zokusingqongileyo ezifana nothuli, umsi, izixhobo zokucoca) kunye neendlela zokucoca.
Esona sithwali siqhelekileyo siqhelekileyo ngabantu. Nokuba neyona mpahla ingqongqo kunye neyona nkqubo ibalulekileyo yokusebenza, abaqhubi abaqeqeshiweyo abaqeqeshiweyo yeyona nto iphambili yongcoliseko kwigumbi lokucoca. Abasebenzi abangalandeliyo izikhokelo zegumbi lokucoca zizinto ezinomngcipheko omkhulu. Ngalo lonke ixesha umqeshwa omnye wenza impazamo okanye alibale inyathelo, iya kukhokelela kungcoliseko lwegumbi lokucoca lonke. Inkampani inokuqinisekisa kuphela ukucoceka kwegumbi lokucoca ngokubeka iliso eliqhumayo kunye nokuqhubeka nokufumana uqeqesho kunye nenqanaba lokungcola.
Eminye imithombo ephambili yongcoliseko zizixhobo kunye nezixhobo. Ukuba inqwelwana okanye umatshini kuphela obekelwe nje ngaphambi kokungena kwigumbi lokucoca, inokuzisa kwi-microorganisms. Rhoqo, abasebenzi abazazi ukuba izixhobo ezinamavili ziqengqeleka ngaphezulu kwendawo engcolisekileyo njengoko ityhala kwigumbi elicocekileyo. Iindawo eziphezulu (kubandakanywa imigangatho, iindonga, izixhobo, njl. Njl.) Zivavanywa rhoqo iipleyiti ezisebenzayo ezisebenzisa i-Agar yoQhakalo enama-Gextrase Agar (SDA). I-TSA iphakathi kokukhula yenzelwe ukuba intsholongwane, kwaye i-SDA yindawo yokukhula yenzelwe ukubumba kunye ne-neasts. I-TSA kunye ne-SDA ziqhelekile kubushushu obahlukeneyo, i-TSA iveze amaqondo obushushu kwiminyaka engama-30-35, engowona ubushushu bokukhula okuphezulu kweBacteria. Uluhlu lwama-20-25ºC luyinto elungileyo kakhulu ye-fold kunye negwele.
I-Airflow yayikukuba sisizathu esiqhelekileyo sokungcoliswa, kodwa iinkqubo zegumbi lokucoca i-HVAC ze-HVAC ziphelise ungcoliseko lomoya. Umoya kwigumbi lokucoca ulawulwa kwaye ubekwe esweni rhoqo (umzekelo, imihla ngemihla, ngeveki, ngekota) ye-isticle, ukubalwa, kunye nokufuma. Iifilitha ze-HEPA zisetyenziselwa ukulawula i-sublecle emoyeni kwaye zinokwazi ukucoca amasuntswana ukuya kwi-0,2μm. Ezi filters zihlala zibaleka ngokuqhubekayo kwinqanaba lokuhamba elilawulayo ukugcina umgangatho womoya kwigumbi. Umswakama uhlala ugcinwa kwinqanaba eliphantsi ukuthintela ukwanda kweentsholongwane ezinjengeebhakteria kunye nokubumba ezikhetha iindawo ezimnyama.
Ngapha koko, olona nqanaba uphakamileyo kunye nolona hlobo luqhelekileyo longcoliseko kwigumbi elicocekileyo ngumqhubi.
Imithombo yolwazi kunye neendlela zokungcoliseka zongcoliseko aziphumi kakhulu kumzi mveliso ukuya kumzi mveliso, kodwa kukho umahluko phakathi kwamashishini ngokubhekisele kumanqanaba anyamezelekileyo kwaye anganyamezelekiyo ongcoliseko. Umzekelo, abavelisi beetafile ezingenakuthelekiswa nanto akufuneki balondoloze inqanaba elifanayo lokucoceka njengabavelisi beearhente ezingenayo ngqo emzimbeni womntu.
Abavelisi bamachiza banonyamezelo olusezantsi lokungcola kwentsholongwane kunabavelisi be-elektroniki ephezulu. Abavelisi be-semicondonductor ovelisa iimveliso ezincinci azikwazi ukwamkela naluphi na ungcoliseko lomsebenzi ukuqinisekisa ukusebenza kwemveliso. Ke ngoko, ezi nkampani zixhalabile ngokusebenza kwemveliso ukuba zifakwe emzimbeni womntu kunye nokusebenza kwe-chip okanye ifowuni yefowuni. Zingaphantsi kakhulu malunga ne-fungus, ifungus okanye ezinye iindlela zongcoliseko lwentsholongwane kwigumbi lokucoca. Kwelinye icala, iinkampani zamayeza zixhalabile malunga nayo yonke imithombo yongcoliseko nefileyo.
Umzi mveliso wamayeza ulawulwa yi-FDA kwaye kufuneka alandele ngokungqongqo imigaqo-nkqubo yemveliso (GMP) ngenxa yokuba iziphumo zongcoliseko kushishino lwamachiza ziyingozi kakhulu. Akufunekanga nje abavelisi beziyobisi kuphela kufuneka baqinisekise ukuba iimveliso zabo azinaziibhakteria, ziyacelwa ukuba zinamaxwebhu kunye nokulandela yonke into. Inkampani ye-Tech ephezulu yeTekhnoloji inokuthumela i-laptop okanye iTV ixesha elide njengoko idlulisela uphicotho lwangaphakathi. Kodwa ayisiyonto ilula kumzi-mveliso wamachiza, yiyo loo nto kubalulekile ukuba inkampani ibe nayo, sebenzisa kunye neenkqubo zokucoca icocekile. Ngenxa yokuqwalaselwa kweendleko, iinkampani ezininzi ziqesha iinkonzo zoncedo lwangaphandle lokucoca iinkonzo zokwenza iinkonzo zokucoca.
Inkqubo ecocekileyo yegumbi elinexabiso lendalo esingqongileyo kufuneka ibandakanye amasuntswana abonakalayo kunye nangokungabonakaliyo. Nangona kungekho mfuneko yokuba bonke abangcolisekileyo kwezi meko zilawulwa zichongwa ziintsholongwane. Inkqubo yokulawula okusingqongileyo kufuneka ibandakanye inqanaba elifanelekileyo lokuchongwa kwentsholongwane yesampula. Zininzi iindlela zokuchonga iintsholongwane ezikhoyo.
Inyathelo lokuqala kwi-Bacterry Ukuchonga, ngakumbi xa kufikwa kwigumbi lokucoca igumbi lokucoca, yindlela ye-GRAM STEAIN, njengoko inokubonelela ngemikhondo emibukisweni kumthombo wongcoliseko lwentsholongwane. Ukuba i-microbial bodwa kunye nokuchonga ibonisa i-GRAM-elungileyo coccocki, ungcoliseko lusenokuba luvela ebantwini. Ukuba ukuhlukaniswa kwentsholongwane kunye nokuchonga ibonisa iintonga ezine-GRAM, ungcoliseko lunokuba lufike eluthulini okanye lube ziintsholongwane. Ukuba ukuhlukaniswa kwentsholongwane kunye nokuchonga kubonisa iintonga ezingalunganga zeGRAM, umthombo wongcoliseko usenokuba uvela emanzini okanye nawuphi na umhlaba omanzi.
Ukuchongwa kwe-rolitic kwigumbi lokucoca amayeza kuyimfuneko kuba inxulumene nemiba emininzi yokuqinisekiswa komgangatho, ezinje ngee-biossay kwiindawo ezinemveliso; Ukuvavanywa kwentsholongwane yeemveliso zokuphela kwentsholongwane; Izinto ezingenagama ezingenangaphambili kwiimveliso ezingenanto kunye namanzi; Ulawulo loMgangatho weTekhnoloji yokuGqibela yoBumbeko kumzi-mveliso we-biotechnology; kunye nokuqinisekiswa kwe-ratical yovavanyo ngexesha lokuqinisekiswa. Indlela ye-FDA yokuqinisekisa ukuba intsholongwane inokuphila kwindawo ethile iya kuba ngakumbi kwaye ixhaphake ngakumbi. Xa amanqanaba ongcoliseko lwentsholongwane engaphezulu kwenqanaba elichaziweyo okanye iziphumo zovavanyo lokungcola zibonisa ungcoliseko, kuyimfuneko ukuqinisekisa ukusebenza kweearhente zokucoca kunye nokuchitheka kunye nokuphelisa imithombo yongcoliseko.
Zimbini iindlela zokubeka iliso kwibala lendalo ecocekileyo:
1. Iiplate zonxibelelwano
Ezi zitya zikhethekileyo zenkcubeko ziqukethe ukuqalisa kokukhula okuphakathi, okulungiselelwe ukuphakama ngaphezu komda wesitya. Isigqubuthelo sokunxibelelana sigubungela umphezulu, kwaye nayiphi na i-microorganisms ebonakalayo kumphezulu iya kubambelela kumphezulu we-Agar kwaye ifakwe. Obu buchule bunokubonisa inani lee-microorganisms ezibonakalayo kumphezulu.
2. Indlela yeSwab
Oku kuyingozi kwaye kugcinwe kulwelo olufanelekileyo lwe-stele. I-Swab isetyenziswa kumphezulu wovavanyo kwaye i-microorganism ichongelwe ngokufumana i-swab kwiphakathi. I-Swabs ihlala isetyenziswa kwimigangatho engalinganiyo okanye kwiindawo ezinobunzima kwisampuli kunye neplate yoqhakamshelwano. I-Swab Sampling ingaphezulu kovavanyo olufanelekileyo.
IXESHA LOKUQALA: I-OCT-21 ukuya kwi-2124